کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2885773 1574198 2016 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A Review of the Potential Local Mechanisms by Which Exercise Improves Functional Outcomes in Intermittent Claudication
ترجمه فارسی عنوان
بازبینی مکانیزم های بالقوه محلی که توسط آن ورزش بهبود نتایج عملکردی را در خرابکاری متناوب
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی

BackgroundIntermittent claudication (IC) is a common condition which is associated with significant quality of life limitation. National Institute for Health and Care Excellence guidelines recommend a group-based supervised exercise program as the primary treatment option for claudication, based on clinical and cost effectiveness. This review aims to assess the mechanisms by which exercise improves outcomes in patients with IC.MethodsMEDLINE, EMBASE, and PubMed were searched using the search strategy “claudication” [AND] “exercise” [AND] “mechanisms.” Searches were limited from 1947 to October 2014. Only full-text articles published in the English language in adults (over 18 years of age) were eligible for the review. Any trial involving a nonsupervised exercise program was excluded. Abstracts identified by the database search were interrogated for relevance and citations from the shortlisted papers were hand searched for relevant references.ResultsThe search yielded a total of 112 studies, of which 42 were duplicates. Forty-seven of the remaining 70 were deemed appropriate for inclusion in the review. Exercise is the first-line treatment for IC. Supervised exercise programs improve walking distances, endothelial and mitochondrial function, muscle strength, and endurance. Furthermore, it leads to a generalized improvement in cardiovascular fitness and overall quality of life.ConclusionsThe mechanism by which exercise improves outcome in claudicants is complicated and multifactorial. Further research is required in this area to fully elucidate the precise and predominant mechanisms and to assess whether targeted exercise program modification maximizes mechanism efficacy and patient outcome.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Annals of Vascular Surgery - Volume 30, January 2016, Pages 312–320
نویسندگان
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