Vein Wall Remodeling after Deep Vein Thrombosis: Differential Effects of Low Molecular Weight Heparin and Doxycycline

Treatment with LMWH or DOXY did not alter the size of deep vein thrombosis, mildly altered thrombus composition, and differentially affected vein wall injury, despite similar reductions in early MMP9 activity. Whether exogenous MMP inhibition affects long-term vein wall fibrosis will require further study.