کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2900306 1173326 2013 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Octreotide : A Drug Often Used in the Critical Care Setting but Not Well Understood
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Octreotide : A Drug Often Used in the Critical Care Setting but Not Well Understood
چکیده انگلیسی

While the canonical function of somatostatin (SST) is to inhibit the secretion of growth hormone, it has a number of other physiologic effects that are less widely appreciated. Octreotide, an analog of SST, is not uncommonly used in the critical care setting, particularly for the treatment of variceal hemorrhage. Herein, we discuss the biology and pharmacology of SST, octreotide, and other SST analogs. We also review the evidence behind their use in esophageal variceal bleeds, hepatorenal syndrome, hypoglycemia due to sulfonylurea poisoning, and chylous pleural effusions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chest - Volume 144, Issue 6, December 2013, Pages 1937–1945
نویسندگان
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