کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2913229 1575487 2011 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Computational Study of Haemodynamic Effects of Entry- and Exit-Tear Coverage in a DeBakey Type III Aortic Dissection: Technical Report
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Computational Study of Haemodynamic Effects of Entry- and Exit-Tear Coverage in a DeBakey Type III Aortic Dissection: Technical Report
چکیده انگلیسی

ObjectivesOutcome prediction in DeBakey Type III aortic dissections (ADs) remains challenging. Large variations in AD morphology, physiology and treatment exist. Here, we investigate if computational fluid dynamics (CFD) can provide an initial understanding of pressure changes in an AD computational model when covering entry and exit tears and removing the intra-arterial septum (IS).DesignA computational mesh was constructed from magnetic resonance images from one patient (one entrance and one exit tear) and CFD simulations performed (scenario #1). Additional meshes were derived by virtually (1) covering the exit tear (false lumen (FL) thrombus progression) (scenario #2), (2) covering the entrance tear (thoracic endovascular treatment, TEVAR) (scenario #3) and (3) completely removing the IS (fenestration) (scenario #4). Changes in flow patterns and pressures were quantified relative to the initial mesh.ResultsSystolic pressures increased for #2 (300 Pa increase) with largest inter-luminal differences distally (2500 Pa). In #3, false lumen pressure decreased essentially to zero. In #4, systolic pressure in combined lumen reduced from 2400 to 800 Pa.ConclusionsCFD results from computational models of a DeBakey type III AD representing separate coverage of entrance and exit tears correlated with clinical experience. The reported results present a preliminary look at a complex clinical problem.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Vascular and Endovascular Surgery - Volume 42, Issue 2, August 2011, Pages 172–177
نویسندگان
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