کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2913271 1575480 2012 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Midterm Outcomes and Risk Stratification after Endovascular Therapy for Patients with Critical Limb Ischaemia due to Isolated Below-the-knee Lesions
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Midterm Outcomes and Risk Stratification after Endovascular Therapy for Patients with Critical Limb Ischaemia due to Isolated Below-the-knee Lesions
چکیده انگلیسی

ObjectivesTo assess and risk stratify midterm clinical outcomes after endovascular therapy (EVT) by angioplasty only of patients with critical limb ischaemia (CLI) due to isolated below-the-knee (BTK) lesions.DesignRetrospective multicenter study.Materials and methodsBetween March 2004 and October 2010, 465 limbs (Rutherford 5 and 6: 79%) from 406 patients were studied. Overall survival, limb salvage, and re-intervention were examined out to 3 years by the Kaplan–Meier method and the log-rank test. Their independent predictors and risk stratification were analysed.ResultsPatient age was 71 ± 11 yrs, with 69% diabetics and 60% on dialysis. Mean follow-up was 18 ± 15 months. Overall survival was 76 ± 2 and 57 ± 4% at 1 and 3, years, respectively. Survival predictors were body mass index <18, non-ambulatory status and ejection fraction <45%. Two-year limb salvage rate was 80 ± 2%. Factors associated with major amputation were ulcers (Rutherford 6), diabetes mellitus, C-reactive protein>5 mg/dL, and age < 60 years. Two-year freedom from re-intervention was 66 ± 3%; age and below-the-ankle runoff number after angioplasty was negatively associated with re-intervention.ConclusionsDespite relatively high mortality and re-intervention rates, limb salvage rate was acceptable after EVT for CLI patients with isolated BTK lesions. Risk stratification allows occurrence estimation for each end point.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Vascular and Endovascular Surgery - Volume 43, Issue 3, March 2012, Pages 313–321
نویسندگان
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