کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2914573 1575512 2009 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Two-End Intimal Flap Suturing Method for Establishing Stanford B Type Aortic Dissection in a Canine Model
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Two-End Intimal Flap Suturing Method for Establishing Stanford B Type Aortic Dissection in a Canine Model
چکیده انگلیسی

ObjectiveTo establish an animal model of Stanford type B aortic dissection using a two-end intimal flap suturing.DesignTwelve adult mongrel dogs of either sex were studied and followed up, at intervals, up to 1 year.Materials and methodsA lateral clamp was placed on the proximal descending aorta after general anaesthesia and left thoracotomy. Half the circumference of the aorta, including the media and adventitia, was cut open transversely, leaving the intima intact. The aortic wall was separated inferiorly. The intima was transversely cut and both ends of the distal intimal flap were sutured to the adjacent aorta. To close, the distal adventitia and media were sutured to the proximal aorta. Before thoracic cavity closure, digital subtraction angiography (DSA) and colour Doppler ultrasound were performed.ResultsFormation and distal extension was observed immediately after removal of the partial aortic clamp in 11 dogs. True and false lumens were seen in eight dogs; the false lumen was larger than the true lumen. Sacrifice at set intervals, 7 days to 12 months after surgery, showed a typical dissection tear, intima, septum, adventitia, thrombi and distal dissection blind pocket.ConclusionThis model of aortic dissection using the two-end aortic intimal flap suturing method is similar to human Stanford type B aortic dissection.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Vascular and Endovascular Surgery - Volume 38, Issue 5, November 2009, Pages 603–607
نویسندگان
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