کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2915062 | 1575530 | 2008 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Prevalence and Risk Factors of PAD among Patients with Elevated ABI Prevalence and Risk Factors of PAD among Patients with Elevated ABI](/preview/png/2915062.png)
ObjectivesTo assess the prevalence and clinical significance of elevated ankle-brachial index (ABI) in patients referred to vascular consultation.DesignRetrospective clinical study.Material and methodsIn 1,762 patients referred with a suspicion of peripheral arterial disease (PAD), ABI and toe brachial index (TBI) were measured by photoplethysmography. ABI ≥ 1.3 was considered falsely elevated and TBI < 0.60 was the diagnostic criterion for PAD.ResultsThe prevalence of elevated ABI was 8.4% and that of PAD among these patients 62.2%. PAD was significantly more prevalent among subjects with severe symptoms (rest pain, ulcers or gangrene) than in those with intermittent claudication (83.8% and 45.3%, respectively, p < 0.001). The risk of PAD diagnosis was ten-fold (OR 10.31, 95% CI 2.07–51.30) among those with chronic renal failure, five-fold among patients with a history of smoking (OR 5.63, 95% CI 1.22–26.00) and over three-fold (OR 3.44, 95% CI 1.46–8.12) among those with coronary heart disease. The specificities of elevated ABI threshold levels (1.3, 1.4 and 1.5) in identifying PAD were 86%, 94% and 96%, respectively, the sensitivities being 44%, 38% and 36%, respectively.ConclusionsThe prevalence of elevated ABI in patients referred to vascular consultation is 8.4% and that of PAD among these 62.2%. PAD is significantly more probable among those with chronic renal failure, a history of smoking and coronary heart disease. Furthermore, the specificity of elevated ABI (≥1.3) in recognizing PAD is good, whereas the sensitivity is only satisfactory.
Journal: European Journal of Vascular and Endovascular Surgery - Volume 35, Issue 6, June 2008, Pages 709–714