کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2915303 1575560 2006 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Assessing the Validity and Responsiveness of Disease-specific Quality of Life Instruments in Intermittent Claudication
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Assessing the Validity and Responsiveness of Disease-specific Quality of Life Instruments in Intermittent Claudication
چکیده انگلیسی

PurposeTo recommend a suitable disease-specific quality of life (QOL) instrument for use in intermittent claudication (IC) based on validity and responsiveness.MethodsSeventy claudicants completed two generic (SF36 and EUROQOL) and three disease-specific (CLAUS, VASCUQOL and SIPIC) QOL instruments prior to and 6 months after treatment (angioplasty or conservative therapy). Ankle brachial pressure indices and treadmill walking distances were measured at each assessment and International Society of Cardiovascular Surgery (ISCVS) recommended outcome measures were used to stratify the results. Construct and convergent-divergent validity was assessed for the three disease-specific QOL instruments. Responsiveness was assessed using effect sizes (effect size >0.5 is clinically significant).ResultsAll clinical indicators improved significantly following treatment. All five domains of CLAUS, the VASCUQOL and SIPIC showed highly significant spearman correlation with intermittent claudication distance (ICD) and maximum walking distance (MWD) (0.267–0.697, p=0.01), suggesting good construct validity. There was greater correlation between like domains of CLAUS and SF36 than non-like domains suggesting good convergent-divergent validity. Pain domain of CLAUS and VASCUQOL could detect mild clinical improvement significantly (effect sizes 0.55 and 0.67). Pain and everyday life domain of CLAUS and the VASCUQOL could detect moderate clinical improvement significantly (effect sizes 0.7, 0.74 and 0.56, respectively).ConclusionThe three disease-specific QOL instruments (CLAUS, VASCUQOL, SIPIC) showed a high degree of construct and convergent-divergent validity. Amongst the three disease-specific QOL instruments, the VASCUQOL was most responsive and we would recommend its use in clinical practice.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Vascular and Endovascular Surgery - Volume 31, Issue 1, January 2006, Pages 46–52
نویسندگان
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