Multi-Modality Guided Trans-Apical Closure of Recurrent Mitral Para-Valvular Regurgitation After Failed Surgical Management in a Patient with Osteogenesis Imperfecta

We report a case of a 54 year-old man with osteogenesis imperfecta who developed severe para-valvular mitral regurgitation after a second heart operation to correct the same problem. The large para-valvular leak was successfully closed with an Amplatzer Vascular Plug III delivered from the apical approach.