کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2924437 | 1175905 | 2006 | 5 صفحه PDF | دانلود رایگان |

BackgroundFar-field extra-pulmonary vein (PV) potentials originating from the left atrial appendage and adjacent left atrium have been identified within the left PVs, but no systematic study of extra-PV potentials within the right superior PV (RSPV) has been described.ObjectivesThe purpose of this study was to prospectively analyze extra-PV contributions to RSPV potentials.MethodsIn a consecutive, prospective series of 114 patients (96 men and 18 women; 56 ± 10 years) undergoing electrophysiologically guided ostial PV isolation, residual potentials recorded with a circular mapping catheter in the RSPV after ostial isolation were analyzed. Their extra-PV origin was validated by mapping a site with identical timing (in sinus rhythm or atrial fibrillation) within the adjacent superior vena cava (SVC) where, in sinus rhythm, local pacing (until threshold amplitude) concealed the residual potential within the stimulus artifact because of very short activation timing. The timing of residual potentials with respect to surface ECG P-wave onset was measured and compared with the earliest timing of ablated RSPV potentials.ResultsResidual low-amplitude (mean 0.29 ± 0.17 mV, range 0.07–0.65 mV) extra-PV potentials were recorded from the anterior and superior aspect of the RSPV in 3.6 ± 1 bipoles in 26 (23%) patients (all men, 51 ± 10 years) with a timing from sinus P-wave onset of 17 ± 12 ms (range 0–40 ms) vs 52 ± 9 ms (range 35–70 ms) for the earliest RSPV potential (P <.001, t-test). Extra-PV potentials all originated from the posterior aspect of the SVC. The SVC potential was identified during ongoing atrial fibrillation in eight patients and later confirmed in sinus rhythm. An extra-PV potential of SVC origin could be identified by timing earlier than 30 ms from onset of the sinus P wave, with sensitivity of 92%, specificity 100%, positive predictive value 100%, and negative predictive value 89%.ConclusionExtra-PV potentials of right-sided SVC origin were recorded within the RSPV in 23% of patients and can be identified with high sensitivity and specificity by a timing within 30 ms of sinus P-wave onset. Recognizing these potentials can avoid unnecessary additional ablation and possibly PV stenosis or phrenic paralysis.
Journal: Heart Rhythm - Volume 3, Issue 8, August 2006, Pages 898–902