کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2934429 | 1576339 | 2008 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: The risk of metabolic syndrome according to the high-sensitivity C-reactive protein in apparently healthy Koreans The risk of metabolic syndrome according to the high-sensitivity C-reactive protein in apparently healthy Koreans](/preview/png/2934429.png)
BackgroundRecently, considerable interest has been focused on the positive relationship between inflammation and the metabolic syndrome (MS). Therefore, we investigated whether the baseline plasma levels of the high-sensitivity C-reactive protein could be associated with future risk for MS in apparently healthy Koreans.MethodsA total of 1132 subjects (767 men, 365 women with a mean age of 49 years), who underwent health examination at this hospital in both 2002 and 2005 were enrolled. The criteria for metabolic syndrome followed that of NCEP-ATP III guideline except waist circumference. Instead, BMI (≥ 25 kg/m2) was used for the measurement for obesity.Results and conclusionsThe relative risks of future MS in the highest quartile of high-sensitivity C-reactive protein at baseline were 2.4 (95% confidence interval [CI], 1.3–4.2) as compared to the subjects in the lowest quartile. Positive associations persisted after adjustment for age, sex and smoking; multivariate relative risks for the highest vs lowest quartiles were 2.3 (95% CI, 1.3–4.1; P for trend = 0.005). This retrospective study suggests that elevated levels of high-sensitivity C-reactive protein could be associated with incident MS.
Journal: International Journal of Cardiology - Volume 129, Issue 2, 26 September 2008, Pages 266–271