کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2935917 | 1576367 | 2007 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
How should the efficacy of novel treatments be assessed in survival trials?
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
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چکیده انگلیسی
Survival trials tend to have the results presented in relative terms, usually using the hazard ratio. When absolute treatment effects are presented this is often done in terms of the Number Needed to Treat concept. For many medical treatments this approach is biologically implausible and can be misleading. The mean survival time approach leading to the absolute treatment effect in terms of extra life years is rarely used. It is suggested that this approach has many advantages over the Number Needed to Treat approach and should be used to present the absolute treatment effect in survival trials.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Cardiology - Volume 120, Issue 3, 3 September 2007, Pages 297-300
Journal: International Journal of Cardiology - Volume 120, Issue 3, 3 September 2007, Pages 297-300
نویسندگان
A. Owen,