کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2936155 1576407 2006 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Continuation of hormone replacement therapy during acute myocardial infarction after the women's health initiative study. Is it the time for change?
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Continuation of hormone replacement therapy during acute myocardial infarction after the women's health initiative study. Is it the time for change?
چکیده انگلیسی

Hormone replacement therapy (HRT) was given for many years in order to relieve menopausal symptoms and was used for as long as symptom control was necessary.The Heart and Estrogen/Progestin Replacement Study (HERS) and Women's Health Initiative (WHI) studies showed that HRT should not be given for primary or secondary prevention of coronary heart disease (CHD). However, what about those patients during acute myocardial infarction who are already taking HRT? Is the ‘don't stop don't start’ rule still true?A 58-year-old white female, on HRT was admitted with acute myocardial infarction (MI). We tried to answer the above questions in light of the new information:1)continuation of HRT during acute MI2)HRT and cardiovascular risk factors3)HRT and coronary revascularization4)HRT and the prevention of acute MIBased on current evidence available from HERS and WHI trials, it is not advisable to initiate HRT in women with established CHD for the sole purpose of preventing first or recurring coronary events. A statement by the American Heart Association recommends that the decision to continue or stop HRT in women with CV disease should be based on established benefits and risks, taking patients preference into account. The WHI study did not change this policy in the acute phase. In most cases, we believe HRT should be continued for some period (our decision for 3 months long was arbitrary), and discontinued gradually. We believe that this should be the policy until we have a double-blind placebo-control data to revise.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Cardiology - Volume 107, Issue 3, 8 March 2006, Pages 293–298
نویسندگان
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