Optical coherence tomography for identifying unstable coronary plaque

This manuscript examines intravascular imaging with optical coherence tomography (OCT). OCT is a potentially attractive intravascular imaging technology due to its high resolution, small catheters/guidewires, and ability to be combined with spectroscopic techniques. Its potential disadvantages remain its limited penetration and signal attenuation by blood. The manuscript reviews unstable plaque, OCT principles, historical development, current challenges, and comparison with IVUS.