Inhibition of renin angiotensin aldosterone system causes abrogation of obliterative airways disease through inhibition of tumor necrosis factor-α-dependant interleukin-17

Our results demonstrate that modulation of RAAS leads to downregulation of IL-17 through tumor necrosis factor-α-dependant IL-6 through p38/MAPKinase pathway and thus abrogation of anti-MHC-induced OAD.