Different prognostic impact of the tissue Doppler-derived E/e′ ratio on mortality in Chagas cardiomyopathy patients with heart failure

This study demonstrated the role of the interaction between LV ejection fraction and E/e′ ratio in predicting prognosis in Chagas cardiomyopathy patients. The E/e′ ratio had a stronger prognostic value in patients with mild and moderate LV dysfunction and was inversely associated with mortality in patients with advanced systolic heart failure.