HLA Sensitization in Pediatric Pre-transplant Cardiac Patients Supported by Mechanical Assist Devices: the Utility of Luminex

Infants supported with ECMO are at low risk for HLA sensitization. Because it provides full antibody specificity disclosure, Luminex complements more conventional PRA assays by quantitatively identifying potential donor-specific antibodies, which should facilitate the virtual crossmatch process, thereby minimizing post-HTx humoral rejection risk.