Regional Heterogeneity of Decreased Myocardial Norepinephrine and Increased Lipid Peroxidation Levels in Patients With End-stage Failing Heart Secondary to Dilated or Ischemic Cardiomyopathy

This study is the first demonstration of a correlation between the values of pre-operative LVEF and cardiac NE concentrations in specific parts of the myocardium. This effect could not be generalized to the entire heart. The pattern of myocardial MDA distribution did not follow that of the NE distribution.