Discordant Changes in Epicardial and Microvascular Coronary Physiology After Cardiac Transplantation: Physiologic Investigation for Transplant Arteriopathy II (PITA II) Study

New coronary physiologic measures, FFR and IMR, show that epicardial artery physiology worsens and correlates with anatomic changes, whereas microvascular physiology improves during the first year after cardiac transplantation. CFR, the traditional method for evaluating coronary circulatory physiology, did not identify these changes.