Prevalence and Prognostic Significance of Anemia in Patients With Congestive Heart Failure Treated With Standard vs High Doses of Enalapril

Low baseline Hct predicted poor 2-year prognosis in patients with CHF. Enalapril administered in high doses increased the incidence of anemia in this population. The underlying pathophysiologic mechanism and effects of maintaining a normal Hct on clinical outcomes remain to be determined.