Tissue Doppler Imaging in Patients with Advanced Heart Failure: Relation to Functional Class and Prognosis

Conventional Doppler indices and TDI parameters correlated with functional class in patients with advanced heart failure. The E/E′ ratio, which probably reflects high LV end-diastolic pressure, was the best measure for differentiating patients with functional class III and IV, and it also correlated with cardiac mortality and hospitalization for worsening heart failure, thereby providing additional value to standard echocardiographic measures.