Changes in Myocardial Vasoreactivity After Drastic Reduction of Plasma Fibrinogen and Cholesterol: a Clinical Study in Long-term Heart Transplant Survivors Using Positron Emission Tomography

Myocardial perfusion in transplanted hearts increases significantly after single HELP-apheresis treatment. The present study is only a proof of concept, providing complementary evidence to clinical long-term studies showing that cholesterol reduction either with statins and/or apheresis improves heart transplant outcome.