Role of thrombolytic therapy in young adult smokers with acute ST-elevation myocardial infarction

Although Percutaneous Coronary Intervention (PCI) has been proven beneficial over TLT in management of acute STEMI, thrombolytics are recanalising the younger patients better than the older patients. TLT has a special place in young smokers as it targets the fibrin breakdown and therefore accounts for higher recanalisation rates, as most of their clots are due to thrombus formation made of fibrin and thrombin.