Biomechanical implications of the congenital bicuspid aortic valve: A finite element study of aortic root function from in vivo data

Aortic valve function is altered in clinically normally functioning bicuspid aortic valves. Bicuspid geometry per se entails abnormal leaflet stress. The stress location suggests that leaflet stress may play a role in tissue remodeling at the raphe region and in early leaflet degeneration.