Dose-response of compression therapy for chronic venous edema-higher pressures are associated with greater volume reduction: Two randomized clinical studies

Pneumatic compression was safe and well-tolerated, with a dose-response relationship between increased SPC/IPC pressures and reduced leg edema. To our knowledge, this is the first study to demonstrate a dose-relationship in compression therapy: higher pressures are associated with greater volume reduction in subjects with chronic venous edema.