Accurate nonfluoroscopic guidance and tip location of peripherally inserted central catheters using a conductance guidewire system

This paper describes impedance technology (a conductance guidewire [CGW]) utilized as a new platform for accurate peripherally inserted central catheter (PICC) line delivery. The CGW has the ability to function as a standard platform for over-the-wire delivery and acts as a novel system for device navigation without the need for fluoroscopy or X-ray. Ultimately, the CGW described here is clinically relevant, as it provides an accurate, anatomically relevant, and reproducible method for PICC delivery that can improve accuracy, decrease the wait time prior to therapy delivery, decrease cost, and minimize X-ray exposure for both patients and clinicians.