کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3008359 | 1181454 | 2013 | 6 صفحه PDF | دانلود رایگان |
AimForce due to leaning during cardiopulmonary resuscitation (CPR) negatively affects haemodynamics and intrathoracic airway pressures (ITP) in animal models and adults, but has not been studied in children. We sought to characterize the effects of sternal force (SF) comparable to leaning force on haemodynamics and ITP in anaesthetized children.MethodsChildren (6 months to 8 yrs) presenting for routine haemodynamic cardiac catheterization with anaesthesia and mechanical ventilation >6 months after cardiac transplant were studied. Haemodynamics and ITP were measured before and during incremental increases in SF of 10% and 20% body weight.Results20 subjects (5.4 ± 1.7 yrs of age and 18.3 ± 3.3 kg) were studied. Mean right atrial pressure (6.5 ± 2.6 at baseline vs. 7.7 ± 2.6 at 10% SF vs. 8.6 ± 2.7 mmHg at 20% SF), mean pulmonary capillary wedge pressure (10.2 ± 2.9 at baseline vs. 11 ± 3.3 at 10% SF vs. 11.8 ± 3.4 mmHg at 20% SF) and ITP (16.3 ± 3.2 at baseline vs. 17.9 ± 3.9 at 10% SF vs. 19.5 ± 4 cm H2O) all increased significantly with incremental SF (p < 0.001 for all). Aortic systolic pressure (85 ± 10 mmHg at baseline vs. 83 ± 10 mmHg at 10% SF vs. 82 ± 10 mmHg at 20% SF, p = 0.014) and coronary perfusion pressure (42 ± 7 mmHg at baseline vs. 39 ± 7 mmHg at 10% SF vs. 38 ± 7 mmHg at 20% SF, p < 0.001) both decreased significantly with incremental SF.ConclusionsIn asymptomatic, anaesthetized children after cardiac transplantation, sternal forces comparable to leaning previously reported to occur during CPR elevate ITP and right atrial pressure and decrease coronary perfusion pressure. These haemodynamic effects may be clinically important during CPR and warrant further study.
Journal: Resuscitation - Volume 84, Issue 12, December 2013, Pages 1674–1679