کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3043974 1184990 2011 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Improving working memory: Exploring the effect of transcranial random noise stimulation and transcranial direct current stimulation on the dorsolateral prefrontal cortex
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Improving working memory: Exploring the effect of transcranial random noise stimulation and transcranial direct current stimulation on the dorsolateral prefrontal cortex
چکیده انگلیسی

ObjectiveThe aim of this study was to determine if working memory (WM) performance is significantly improved after the delivery of transcranial random noise stimulation (tRNS) to the left dorsolateral prefrontal cortex (DLPFC), compared to an active comparator or sham.MethodsTen participants undertook three experimental sessions in which they received 10 min of anodal tDCS (active comparator), tRNS or sham tDCS whilst performing the Sternberg WM task. Intra-stimulation engagement in a WM task was undertaken as this has been previously shown to enhance the effects of tDCS. Experimental sessions were separated by a minimum of 1 week. Immediately prior to and after each stimulation session the participants were measured on speed and accuracy of performance on an n-back task.ResultsThere was significant improvement in speed of performance following anodal tDCS on the 2-back WM task; this was the only significant finding.ConclusionsThe results do not provide support for the hypothesis that tRNS improves WM. However, the study does provide confirmation of previous findings that anodal tDCS enhances some aspects of DLPFC functioning. Methodological limitations that may have contributed to the lack of significant findings following tRNS are discussed.SignificanceAnodal tDCS may have significant implications for WM remediation in psychiatric conditions, particularly schizophrenia.


► Anodal tDCS improves speed of accuracy of WM performance on the 2-back task.
► tRNS does not affect WM performance.
► Anodal tDCS may have significant implications for WM remediation in psychiatric conditions, particularly schizophrenia.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Neurophysiology - Volume 122, Issue 12, December 2011, Pages 2384–2389
نویسندگان
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