کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3046038 1185035 2009 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Reproducibility and clinical relevance of quantitative EEG parameters in cerebral ischemia: A basic approach
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Reproducibility and clinical relevance of quantitative EEG parameters in cerebral ischemia: A basic approach
چکیده انگلیسی

ObjectiveTo investigate reproducibility and clinical relevance of quantitative EEG parameters in ischemic cerebrovascular disease.MethodsEEG was recorded in 31 patients suffering from subacute ischemic cerebrovascular disease. Ten age-matched control subjects were included as a reference group. Intra-recording, intrarater and interrater reproducibility was calculated for standard EEG measures and for a pair wise derived Brain Symmetry Index (pdBSI). Correlations between EEG parameters, clinical status and volume of ischemia on diffusion weighted imaging (DWI) were calculated.ResultspdBSI was sensitive to asymmetry in the amplitude and frequency domain in a random white noise model and in a simulated sinusoidal model. Minimal Cronbach alpha for intra-recording, intra- and inter-rater reproducibility ranged between 0.95 and 0.99 for standard spectral parameters and between 0.96 and 0.99 for pdBSI. We found a significant difference in pdBSI between stroke patients and control or TIA (p = 0.0003). pdBSI correlated significantly with NIH stroke scale at admission and DWI volume across different levels of stroke probability (Spearman’s ρ = 0.64–0.70 and 0.79–0.84, respectively, p < 0.00001 for both).ConclusionspdBSI displays high multilevel reproducibility and reliably discriminates between stroke and TIA patients or control subjects, and correlates significantly with clinical and radiological status.SignificanceBased on this methodological analysis, reliable EEG parameters can be evaluated in a general stroke population for clinically relevant state and outcome measures.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Neurophysiology - Volume 120, Issue 5, May 2009, Pages 845–855
نویسندگان
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