کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3046524 1185044 2009 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The impact of chronic primary insomnia on the heart rate – EEG variability link
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
The impact of chronic primary insomnia on the heart rate – EEG variability link
چکیده انگلیسی

ObjectiveTo determine if chronic insomnia alters the relationship between heart rate variability and delta sleep determined at the EEG.MethodsAfter one night of accommodation, polysomnography was performed in 14 male patients with chronic primary insomnia matched with 14 healthy men. ECG and EEG recordings allowed the determination of High Frequency (HF) power of RR-interval and delta sleep EEG power across the first three Non Rapid Eye Movement (NREM)–REM cycles. Interaction between normalized HF RR-interval variability and normalized delta sleep EEG power was studied by coherency analysis.ResultsPatients showed increased total number of awakenings, longer sleep latency and wake durations and shorter sleep efficiency and REM duration than controls (p < .01). Heart rate variability across first three NREM–REM cycles and sleep stages (NREM, REM and awake) were similar between both groups. In each group, normalized HF variability of RR-interval decreased from NREM to both REM and awake. Patients showed decreased linear relationship between normalized HF RR-interval variability and delta EEG power, expressed by decreased coherence, in comparison to controls (p < .05). Gain and phase shift between these signals were similar between both groups.ConclusionsInteraction between changes in cardiac autonomic activity and delta power is altered in chronic primary insomniac patients, even in the absence of modifications in heart rate variability and cardiovascular diseases.SignificanceThis altered interaction could reflect the first step to cardiovascular disorders.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Neurophysiology - Volume 120, Issue 6, June 2009, Pages 1054–1060
نویسندگان
, , , , , , , ,