کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3047672 1185062 2006 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
EEG findings in early-stage corticobasal degeneration and progressive supranuclear palsy: A retrospective study and literature review
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
EEG findings in early-stage corticobasal degeneration and progressive supranuclear palsy: A retrospective study and literature review
چکیده انگلیسی

ObjectiveAlthough neuroimaging and electrophysiological tests are potentially useful to distinguish corticobasal degeneration (CBD) from progressive supranuclear palsy (PSP), little is known about the diagnostic value of electroencephalography (EEG) for their distinction. We assessed the value of EEG for differentiating CBD from PSP.MethodsWe reviewed conventional EEGs recorded at an early stage of disease in 10 CBD patients and 14 PSP patients. We focused on slowing of background activity (SBA), frontal intermittent rhythmic delta activity (FIRDA) and focal slow waves (FSWs). Statistical analysis was performed by Fisher’s exact test.ResultsSBA was observed in 1 CBD patient and 2 PSP patients. FSWs were found in 8 CBD patients (80.0%), but only 2 PSP patients (14.3%) (p = 0.002); they appeared contralateral to the dominantly-affected side in 6 of 8 CBD patients, and ipsilateral to the side with most atrophy on MRI in 7 of 8 CBD patients. FIRDA was observed in 2 CBD patients (20.0%) and 5 PSP patients (35.7%) (p = 0.357).ConclusionsFSWs are characteristic of CBD, but FIRDA was not disease-specific.SignificanceFSWs on EEG, in addition to clinical criteria, yield useful supplementary information to distinguish between these diseases at early stages.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Neurophysiology - Volume 117, Issue 10, October 2006, Pages 2236–2242
نویسندگان
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