Cost and cost-effectiveness analysis of a bundled intervention to enhance outcomes after stroke in Nigeria: Rationale and design

• Provides evidence on stroke costs towards improving treatment of stoke survivors
• Two evaluation methods -cost-effectiveness and cost–benefit analysis proposed
• Study to be conducted in four Nigerian hospitals with 400 patients as participants
• THRIVES Post-discharge intervention compared with control intervention scenario
• Successful outcome of THRIVES project will indicate cost-effective stroke care.

The economic and social costs of stroke to the society can be enormous. These costs can cause serious economic damage to both the individual and the nation. It is thus important to conduct a cost effectiveness analysis to indicate whether an intervention provides high value where its health benefits justify its costs. This study will provide evidence based on the costs of stroke with a view of improving intervention and treatments of stoke survivors in Nigeria.This study utilizes two types of economic evaluation methods – cost-effectiveness analysis and cost–benefit analysis – to determine the economic impact of Tailored Hospital-based Risk Reduction to Impede Vascular Events after Stroke (THRIVES) intervention. The study is conducted in four Nigerian hospitals where 400 patients are recruited to participate in the study. The cost-effectiveness of THRIVES post-discharge intervention is compared with the control Intervention scenario, which is the usual and customary care delivered at each health facility in terms of cost per quality adjusted life years (QALYs). It is expected that successful implementation of the project would serve as a model of cost-effective quality stroke care for implementation.Award Number: U01 NS079179.Trial registration: RL: http://www.clinicaltrials.gov. Unique identifier: NCT01900756