کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3052261 | 1186091 | 2012 | 7 صفحه PDF | دانلود رایگان |

SummaryPurposeThis study characterized the demographic, clinical, EEG and imaging profile, and therapeutic outcome among patients with hot water epilepsy (HWE).Methodology This prospective study included 70 patients with HWE (M:F = 55:15; age: 25.3 ± 8.4 years). Details of demography, seizure characteristics and outcome, and imaging/EEG observations were recorded.ResultThere was male dominance. Majority of the patients belonged to Mandya: 30.5%, Ramanagara: 30.0% and Mysore: 15.2% districts of Karnataka, India. Forty-five patients (M:F = 37:8; age: 24.6 ± 10.1 years) had features of ‘HWE alone’. Twenty-five (M:F = 18:7; age: 26.7 ± 7.9 years) had HWE with spontaneous seizures. The age at onset of seizures was comparable in both the groups – HWE: 18.7 ± 10.2 years vs. HWE with spontaneous seizure: 16.8 ± 10.3 years (p = 0.34). The duration of seizures were more in HWE with spontaneous seizure group: 119.5 ± 66.9 months compared to HWE alone: 69.9 ± 13.8 months (p = 0.028). Inter-ictal EEG (n = 70) showed epileptiform activities in 15 patients (21.4%). The therapeutic outcome after 3–8 months of follow up were – (a) HWE group: 6 stopped hot water head bath; 39 were on intermittent clobazam therapy – seizure free: 33; and 6 received AEDs; (b) HWE with spontaneous seizure group: all were on AEDs and seizure free.ConclusionsThree-fourth of patients belonged to ‘Mandya–Mysore belt of Karnataka’. There was increased duration of seizures among those with additional spontaneous seizure. About 3/4th subjects with HWE alone were seizure free with intermittent clobazam and remaining patients on AEDs were seizure free, confirming the earlier observations from this center.
Journal: Epilepsy Research - Volume 102, Issue 3, December 2012, Pages 160–166