Long term outcomes in patients with preoperative generalized interictal epileptiform abnormalities following amygdalohippocampectomy

We evaluated long term surgical outcomes in 21 patients with temporal lobe epilepsy and presurgical generalized interictal epileptiform discharges (IEDs). Following amygdalohippocampectomy, 12 patients (57.1%) were noted to have favorable outcomes (Engel classification of I-II). Favorable outcomes were significantly associated with a history of auras prior to seizure onset (p = 0.021), the absence of generalized IEDs on postoperative EEG (p = 0.024), and the presence of focal slowing on postoperative EEG (p = 0.045).