کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3054241 1580041 2011 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Performance on Wechsler intelligence scales in children with Tourette syndrome
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب تکاملی
پیش نمایش صفحه اول مقاله
Performance on Wechsler intelligence scales in children with Tourette syndrome
چکیده انگلیسی

BackgroundThere is some evidence that Tourette syndrome is associated with cognitive disabilities.AimsTo examine the cognitive performance of a clinical cohort of children with Tourette syndrome.Methods266 children with Tourette syndrome have been examined with Wechsler Intelligence Scales. The presence of the co-morbidities attention deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD) was assessed using validated diagnostic instruments. Eighty healthy controls matched a part of the TS cohort.ResultsThe children with Tourette syndrome had a mean verbal IQ (VIQ) of 92.9, performance IQ (PIQ) of 87.1, and full-scale IQ (FSIQ) of 88.8. We found statistically significant higher PIQ and FSIQ in the control group compared with a matched TS cohort and a trend towards a higher VIQ among the healthy controls. There was a statistically significant influence of age at onset of tics on PIQ. The children with co-morbid OCD scored higher on FSIQ compared with the other groups. The children with co-morbid ADHD and OCD showed problems in motor tasks and speed tasks and the children with co-morbid ADHD showed attention deficits.ConclusionsChildren with Tourette syndrome have lower IQ scores than the general population (but less than one standard deviation below) and our control group. Early onset of tics and the presence of co-morbidities might cause specific deficits on cognitive performance.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Paediatric Neurology - Volume 15, Issue 2, March 2011, Pages 146–154
نویسندگان
, , , , ,