کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3058920 | 1187416 | 2015 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Multimodality management of a giant skull base hemangioendothelioma of the sphenopetroclival region Multimodality management of a giant skull base hemangioendothelioma of the sphenopetroclival region](/preview/png/3058920.png)
A 20-year-old man presented with proptosis, nasal obstruction, vision loss and cavernous sinus syndrome, ongoing for 6 years. Imaging and biopsy confirmed a middle skull base epithelioid hemangioendothelioma arising from the left sphenopetroclival region with infratemporal fossa and intracranial-intradural extension into the left temporal lobe. Preoperative embolization of the left internal maxillary artery followed by a combined neurosurgical (front-temporal orbito-zygomatic craniotomy) and otorhinolaryngology (maxillary swing) approach was performed for tumor debulking. Postoperative radiotherapy and maintenance interferon chemotherapy was given to achieve a favorable outcome at 6 months follow-up. We describe the pertinent clinical, genetic, radiological and histopathological features, along with the available therapeutic modalities for a primary giant skull base hemangioendothelioma.
Journal: Journal of Clinical Neuroscience - Volume 22, Issue 9, September 2015, Pages 1495–1498