کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3059023 1187419 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Three-year prognosis of first-ever primary pontine hemorrhage in a hospital-based registry
ترجمه فارسی عنوان
پیش آگهی سه ساله اولین خونریزی اولیه پونتین در یک رجیستر مبتنی بر بیمارستان
کلمات کلیدی
مرگ و میر پیشگو، خونریزی اولیه پونتین، پیش بینی
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
چکیده انگلیسی

Our aim was to evaluate the mortality rate of primary pontine hemorrhage (PPH) and to determine the factors related to the prognosis. Limited data exist on the long-term prognosis and determinants of death in patients with PPH in China. Our study analyzed consecutive cases of first-ever PPH from April 2007 to March 2011 in a hospital-based stroke registry. Mortality rates during 30 day and 3 year follow-ups were analyzed. We used the Kaplan–Meier method to estimate the event rates and binary logistic regression analysis, and Cox proportional hazard regression analysis to identify predictors of short-term and long-term prognosis, respectively. A total of 76 patients were identified, 44 (57.89%) were men. Both 30 day and 3 year overall mortalities in men were higher than women but this different was not statistically significant. Coma on admission, hematoma ⩾4 mL and a massive hemorrhage were significantly related to 30 day mortality of PPH. Multivariate Cox proportional hazard regression revealed that coma on admission (hazard ratio [HR] 2.18; 95% confidence interval [CI] 1.16–4.13; p = 0.02) and hematoma ⩾4 mL (HR 2.23; 95% CI 1.25–3.96; p = 0.01) were independent predictors of 3 year mortality. In conclusion, the short-term mortality rate and factors related to the prognosis of Chinese patients with PPH are similar to those reported for other populations. A low Glasgow coma scale score on admission and a large hematoma volume may be related to poor 3 year prognosis after PPH.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical Neuroscience - Volume 22, Issue 7, July 2015, Pages 1133–1138
نویسندگان
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