کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3062100 1187485 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Interleukin-5 and interleukin-10 are produced in central nervous system tumor cysts
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Interleukin-5 and interleukin-10 are produced in central nervous system tumor cysts
چکیده انگلیسی

Interleukin-5 and interleukin-10, as important mediators of vascular permeability, contribute to the development of various pathologic effusions. However, little is known regarding the involvement of these two cytokines in the formation of cysts associated with central nervous system (CNS) tumors. Twenty-eight patients with various cystic CNS tumors were investigated for expression of interleukin-5 and interleukin-10 in cyst fluid and their matched cytokine receptors in tumor tissue. Interleukin-5 and interleukin-10 were detected in cyst fluid, and interleukin-5 concentration was significantly correlated with interleukin-10 concentration (r = 0.508, p = 0.006). Moreover, both receptors were also detectable in the tumor tissue specimens and high levels of expression were also found in perivascular cells. Therefore, the local production of interleukin-5 and interleukin-10 might be implicated in some types of cyst formation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical Neuroscience - Volume 16, Issue 3, March 2009, Pages 437–440
نویسندگان
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