کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3085148 1189798 2013 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Arrhythmogenic Channelopathy Syndromes Presenting as Refractory Epilepsy
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب تکاملی
پیش نمایش صفحه اول مقاله
Arrhythmogenic Channelopathy Syndromes Presenting as Refractory Epilepsy
چکیده انگلیسی

BackgroundChildren and young adults with potentially lethal cardiac channelopathies often present to medical care with a history of syncope or seizures due to episodic ventricular arrhythmias and associated cerebral hypoperfusion.MethodsTwo important types of genetic arrhythmia syndromes—long QT syndrome and catecholaminergic polymorphic ventricular tachycardia—are discussed using relevant case examples. The pathophysiology and distinguishing clinical features of these conditions are reviewed.ResultsThe patients in each case were ultimately diagnosed with a cardiac channelopathy as the cause for their syncope and refractory seizures. With appropriate medical management, no further events have occurred to date.ConclusionsCardiac channelopathies can be misdiagnosed as refractory epilepsy when in fact these events represent convulsive syncopes. Knowledge of and suspicion for these arrhythmogenic conditions may expedite diagnosis and improve outcomes.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pediatric Neurology - Volume 49, Issue 2, August 2013, Pages 134–137
نویسندگان
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