کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3091245 1190344 2006 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The Diverse Clinical Manifestations of Tuberous Sclerosis Complex: A Review
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب تکاملی
پیش نمایش صفحه اول مقاله
The Diverse Clinical Manifestations of Tuberous Sclerosis Complex: A Review
چکیده انگلیسی

Tuberous sclerosis complex (TSC) is an autosomal dominant multisystem neurocutaneous disorder. TSC results in hamartomatous lesions primarily involving the skin, central nervous system, kidneys, eyes, heart, and lungs. The clinical findings and severity of TSC are highly variable. Recent advances in our understanding of the complexities of the TSC1 and TSC2 genes are making genotype-phenotype correlations possible. While managing seizures, cognitive dysfunction, and behavioral abnormalities are the primary responsibility of the neurologist, familiarity with all aspects of this disease helps provide better comprehensive care for affected individuals.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Pediatric Neurology - Volume 13, Issue 1, March 2006, Pages 27–36
نویسندگان
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