کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3097849 1581497 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Comprehensive Evaluation of Powdered Chinese Herbal Medicines-An Exemplification of Isatidis Radix
ترجمه فارسی عنوان
بررسی جامع از داروهای گیاهی پودر شده چینی؛ تمثل ریشه Isatidis
کلمات کلیدی
انحلال شیمیایی؛ ارزیابی جامع؛ Isatidis ریشه؛ زیست سنجی مبتنی بر نورآمینیداز ؛ خصوصیات فیزیکی؛ پودر طب گیاهی چینی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی طب مکمل و جایگزین
چکیده انگلیسی

ObjectiveCurrently, powdered Chinese herbal medicines (CHMs) were mainly evaluated through physical property, chemical dissolution, and bioactivity independently. It could not reflect the quality comprehensively. This paper was to explore and establish a comprehensive evaluation method for powdered CHMs.MethodsIsatidis Radix was chosen as an exemple. Firstly, powdered Isatidis Radix in different particle size was prepared. Then, their physical properties were characterized. The dissolution of index component epigoitrin was determined, and their antiviral activities were evaluated by neuraminidase-based bioassay.ResultsAs the particle size decreased, powder distribution tended to be uniform, and the dissolution of epigoitrin increased, antiviral activity enhanced. According to cluster analysis of above results, the sequence of evaluation consequence was ultrafine powder S2 (D90: 32.80 ± 0.29) > ultrafine powder S1 (D90: 52.08 ± 0.53) > fine powder S0 (D90: 118.16 ± 0.76) (from the superior to the inferior).ConclusionOverall, the comprehensive evaluation for powdered CHMs based on the physical characterization, chemical dissolution, and bioassay could not only be used to evaluate powdered herbs, but also guide the screening and optimization of the particle size of powder.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Herbal Medicines - Volume 8, Issue 3, July 2016, Pages 286–292
نویسندگان
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