کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3099352 1191100 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
An 8-wk, randomized, double-blind, placebo-controlled clinical trial for the antidiabetic effects of hydrolyzed ginseng extract
ترجمه فارسی عنوان
یک کارآزمایی بالینی تصادفی دو سوکور، کنترل شده با پلاسبو 8 روزه برای اثرات ضددردی عصاره جین سنگ هیدرولیز شده
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی طب مکمل و جایگزین
چکیده انگلیسی

BackgroundTo investigate the antidiabetic effects of hydrolyzed ginseng extract (HGE) for Korean participants in an 8-wk, randomized, double-blinded, placebo-controlled clinical trial.MethodsImpaired fasting glucose participants [fasting plasma glucose (FPG) ≥ 5.6mM or < 6.9mM] who had not been diagnosed with any disease and met the inclusion criteria were recruited for this study. The 23 participants were randomly divided into either the HGE (n = 12, 960 mg/d) or placebo (n = 11) group. Outcomes included measurements of efficacy (FPG, postprandial glucose, fasting plasma insulin, postprandial insulin, homeostatic model assessment-insulin resistance, and homeostatic model assessment-β) and safety (adverse events, laboratory tests, electrocardiogram, and vital signs).ResultsAfter 8 wk of HGE supplementation, FPG and postprandial glucose were significantly decreased in the HGE group compared to the placebo group. No clinically significant changes in any safety parameter were observed. Our study revealed that HGE is a potent antidiabetic agent that does not produce noticeable adverse effects.ConclusionHGE supplementation may be effective for treating impaired fasting glucose individuals.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Ginseng Research - Volume 38, Issue 4, 15 October 2014, Pages 239–243
نویسندگان
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