Patterns of sedentary time and cardiometabolic risk among Canadian adults

• Total sedentary time was associated with insulin and diastolic blood pressure.
• ≥ 20 minute sedentary bouts were associated with insulin and diastolic blood pressure.
• Breaks in sedentary time was associated with several cardiometabolic biomarkers.
• Breaking up sedentary time may be particularly important for cardiometabolic health.

ObjectiveThe aim of this study is to examine the associations of total sedentary time and patterns of sedentary time with cardiometabolic biomarkers in a large representative sample of Canadian adults.MethodsThe study is based on 4935 adults aged 20–79 years, from the 2007/09 and 2009/11 Canadian Health Measures Survey. Total sedentary time, patterns of sedentary time (≥ 20 minute prolonged sedentary bouts, number of sedentary breaks), and moderate- to vigorous-intensity physical activity (MVPA) were accelerometer-derived. Waist circumference, systolic and diastolic blood pressure, high-density lipoprotein (HDL) cholesterol, and C-reactive protein were measured. Triglycerides, low-density lipoprotein (LDL) cholesterol, insulin, and glucose were also measured in a fasting sub-sample (n = 2551).ResultsTotal sedentary time and time in ≥ 20 minute prolonged sedentary bouts were associated with higher insulin and lower diastolic blood pressure levels (P < 0.05). On average, each additional 10 breaks/day was associated with 0.83 (95%CI: 1.35, 0.31) cm lower waist circumference, 0.32 (0.62, 0.02) mm Hg lower systolic blood pressure, 0.01 (0.00, 0.02) mmol/l higher HDL-cholesterol, 3.72 (1.34, 6.13) % lower triglycerides, 0.57 (0.23, 0.92) % lower glucose, and 4.19 (1.80, 6.63) % lower insulin.ConclusionThese findings in a large representative sample of Canadian adults indicate that breaking up sedentary time may be particularly important for cardiometabolic health.