Rates and correlates of influenza vaccination among HIV-infected adults in the HIV Outpatient Study (HOPS), USA, 1999–2008

BackgroundWe sought to describe rates of vaccination among HIV-infected adults in care and identify factors associated with vaccination.MethodsUsing data abstracted from medical records of participants in the HIV Outpatient Study (HOPS) during 8 influenza seasons (1999–2008) and negative binomial models with generalized estimating equation methods, we examined factors associated with increased prevalence of annual influenza vaccination.ResultsAmong active patients, 25.8% to 43.3% were vaccinated for influenza each year (annual mean = 35%, test for trend p = 0.71). Vaccination rates peaked in October and November of each season and decreased sharply thereafter. In multivariable analysis, patients who were male (67.2%), non-Hispanic white (70%) or Hispanic (66%), had lower HIV viral loads (73.5%), were prescribed antiretroviral treatment (72.7%), or had a greater number of clinical encounters per year (86.7%) were more likely to receive influenza vaccination.DiscussionThe decreased likelihood of vaccination among women and non-Hispanic black patients suggests the need for focused efforts to reduce disparities. Increasing patient and clinician education on the importance of universal vaccination, and ensuring that vaccination activities continue in HIV clinics during the later months of the influenza season may improve influenza vaccine coverage.

► Describe rates of vaccination among HIV-infected adults in care.
► data abstracted from medical records during 8 influenza seasons (1999–2008)
► 25% to 43% of patients were vaccinated for influenza each year
► decreased likelihood of vaccination among women and non-Hispanic black patients