کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3109735 | 1581980 | 2016 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Central and peripheral manifestations of anti-VGKC antibody-Limbic encephalitis and Morvan's syndrome
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
مراقبت های ویژه و مراقبتهای ویژه پزشکی
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چکیده انگلیسی
Anti-voltage-gated potassium channel antibodies (anti-VGKC) cause hyperexcitability of the peripheral nerve and central nervous system. Morvan's syndrome is characterized by widespread neurological symptoms involving the peripheral nervous system (neuromyotonia), autonomic, and the central nervous system. Limbic encephalitis typically presents with subacute onset of amnesia, behavioral disturbance, psychiatric symptoms, seizures, and altered consciousness. Both Morvan's syndrome and limbic encephalitis have been noted to bear a striking similarity in terms of clinical presentation, association with tumor, and response to immunosuppressive therapy. Both these conditions have been found to be associated with anti-VGKC antibody. Here, we intend to present two cases, one with predominantly peripheral and the other with central manifestation associated with anti-VGKC antibody describing the clinical spectrum of VGKC antibody associated disorders.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Indian Journal of Medical Specialities - Volume 7, Issue 1, JanuaryâMarch 2016, Pages 50-53
Journal: Indian Journal of Medical Specialities - Volume 7, Issue 1, JanuaryâMarch 2016, Pages 50-53
نویسندگان
Chandra Mohan Sharma, Rajendra Kumar Pandey, Banshi Lal Kumawat, Dinesh Khandelwal,