کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3125464 1583776 2008 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Processed bovine dentine as a bone substitute
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Processed bovine dentine as a bone substitute
چکیده انگلیسی

ObjectivesDifferent forms of allogenic dentine have been studied for their potential use as bone substitutes. We report a new method for processing bovine dentine that results in a sterile bioactive material for repair and regeneration of bone.MethodsExtracted bovine dentine was processed mechanically and chemically with inorganic and organic solvents, and sterilised. The in vitro biocompatibility on human gingival fibroblasts was assessed by the Alamar Blue assay and the in vivo biocompatibility evaluated by implantation of the processed dentine into rats’ femurs.ResultsThe dentine showed excellent biocompatibility in vitro, stimulated formation of new bone and was completely incorporated into the new bone in vivo.SignificanceProcessed bovine dentine has the potential to be used as a suitable substitute in bone repair and regeneration.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: British Journal of Oral and Maxillofacial Surgery - Volume 46, Issue 2, March 2008, Pages 110–113
نویسندگان
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