کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3131809 1584114 2016 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Watchful waiting of the neck in early stage oral cancer is unfavourable for patients with occult nodal disease
ترجمه فارسی عنوان
انتظارات سرپایی در مراحل ابتدایی سرطان دهان، برای بیماران مبتلا به بیماری دندانی مخفی، نامطلوب است
کلمات کلیدی
کارسینوم سلول سنگفرشی دهانی، محصور گردن انتخابی، منتظر انتظار، متاستاز، گسترش فوق العاده کپسول
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
چکیده انگلیسی

For cT1/2N0 oral squamous cell carcinoma (OSCC), treatment of the neck is a matter of debate. Two treatment strategies were evaluated in this study: selective neck dissection (SND) and watchful waiting (WW). One hundred and twenty-three SND patients and 70 WW patients with cT1/T2N0M0 OSCC of the tongue, floor of mouth, or buccal mucosa were analysed retrospectively. Extracapsular spread (ECS), 3-year overall survival (OS), and disease-specific survival (DSS) were determined. Twenty-nine percent of SND patients and 13% of WW patients had occult nodal disease. WW-N+ patients showed thicker tumours as compared to WW-N0 patients (5 mm vs. 2 mm, P = 0.02). WW-N+ patients showed significantly more ECS as compared to SND-N+ patients (56% vs. 14%, P = 0.016) and had a significantly worse 3-year DSS than SND-N+ patients (56% vs. 82%, P = 0.02). For T1 OSCCs, a watchful waiting policy is acceptable if tumour thickness proves to be <4 mm. Otherwise, an additional treatment of the neck is advised, since WW-N+ patients show more ECS, with a worse DSS than SND-N+ patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Oral and Maxillofacial Surgery - Volume 45, Issue 8, August 2016, Pages 945–950
نویسندگان
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