کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3133153 1584168 2012 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Masseter muscle fibre changes following reduction of masticatory function
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Masseter muscle fibre changes following reduction of masticatory function
چکیده انگلیسی

This study evaluated histological changes in masseter muscle fibres following reduced masticatory function by injection of botulinum toxin type A (BTX). Sixty 30-day-old Long-Evans male rats were randomly separated into four groups (15 per group): group I BTX masseter, 25 U/ml (0.04 ml each muscle) BTX was injected in bilateral masseter muscle whilst bilateral temporalis muscles received an equal amount of normal saline; group II BTX temporalis, 25 U/ml (0.04 ml each muscle) BTX was injected in bilateral temporalis muscle whilst bilateral masseter muscle received an equal amount of normal saline; group III BTX temporalis and masseter, bilateral temporalis and masseter were given 25 U/ml (0.04 ml each muscle) BTX; group IV normal saline (control), bilateral temporalis and masseter were given normal saline (0.04 ml each muscle). After 45 days, the rats were killed, the muscles dissected and mean muscle mass recorded. The superficial masseter muscles were immunohistochemically analysed. Fibre sizes in group III were bigger than those in other groups. There was a small percentage of type IIa fibres in group III. Reduction in muscle fibre size and transition of muscle fibre subtypes from type IIa to IIx or IIb fibres may occur due to reduced masticatory function.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Oral and Maxillofacial Surgery - Volume 41, Issue 3, March 2012, Pages 394–399
نویسندگان
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