Anatomical Study on Renal Agenesis

Congenital absence of kidney, unilateral or bilateral, is reported to be 1:1000 and 1:10000 births respectively. Unilateral agenesis is an ultrasonagraphic finding in adult with compensatory hypertrophy of the solitary kidney. Renal agenesis is generally associated with genitourinary anomalies like defective Mullerian duct, unilateral/bilateral absence or hypoplasia of seminal vesicle, vas deferens and adrenal agenesis. Unilateral agenesis is also reported to occur in X-linked Kallmann's syndrome. The present case is of a 33 weeks old male fetus medically terminated on the basis of ultrasonagraphy report of anhydraminos and suspected bilateral renal agenesis. Autopsy findings showed left unilateral agenesis, with dilation of the pelvic part of ureter and cryptorchidism on the same side. A study on microstructure of kidney, ureter, vas deferens, seminal vesicle, testes and suprarenal were carried out to observe the structural details.