کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3149164 | 1197437 | 2007 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
In Vitro Activity of Amoxicillin, Clindamycin, Doxycycline, Metronidazole, and Moxifloxacin Against Oral Actinomyces
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
دندانپزشکی، جراحی دهان و پزشکی
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چکیده انگلیسی
Actinomyces spp have been increasingly associated with endodontic infections. However, the antimicrobial susceptibility of this genus has not been studied extensively. The objective of this study was to determine the susceptibility of oral isolates of Actinomyces naeslundii, Actinomyces gerencseriae, Actinomyces israelii, Actinomyces viscosus, and Actinomyces odontolyticus to amoxicillin, clindamycin, doxycycline, metronidazole, and moxifloxacin using in vitro assays. The minimum inhibitory concentration (MIC) of each bacterial isolate was determined by using E-test strips (AB Biodisk, Solna, Sweden). The MIC90 was 0.19 μg/mL for amoxicillin, 0.25 μg/mL for doxycycline, 0.50 μg/mL for moxifloxacin, and 1.00 μg/mL for clindamycin. However, metronidazole was not active against any of the Actinomyces spp tested (MIC90 > 256 μg/mL).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Endodontics - Volume 33, Issue 5, May 2007, Pages 557-560
Journal: Journal of Endodontics - Volume 33, Issue 5, May 2007, Pages 557-560
نویسندگان
Demetrick W. DMD, Frank J. DMD, Maria F. DMD, Ann PhD, Myriam PhD,